Police said six people left the home. Four of them, a 28-year-old woman, a 27-year-old woman, 24-year-old woman and a 27-year-old man, were charged with threatening and attempting to commit murder.
After obtaining a search warrant, police said an imitation handgun, bladed weapons and a needle were found.
Twenty-seven-year-old Kelly Delbert, 27-year-old Janay Adele Sunshine Keewatin, 28-year-old Morgan Chance Littlechief and 24-year-old Amanda Gusnowski, all of Regina, were charged with attempting to commit murder and uttering threats.
Keewatin and Littlechief were also charged with failing to comply with an undertaking, while Gusnowski was charged with failing to comply with a probation order.
All four people appeared in court Monday morning.
Correction: An earlier police report indicated the accused were charged with attempted murder. A correction was issued by Regina police.